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doi: 10.1371/journal.pone.0004416 20 ReedsPJBurrinDGStollBJahoorF

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Engineered 5-HT producing gut probiotic improves gastrointestinal motility and behavior disorder

Another placebo-controlled trial in 320 primary Sjgren patients using the same dosage for 24 weeks found that total glucosides of peony improved patient-reported Sjgren's syndrome index more than placebo, as well as improving erythrocyte sedimentation rate, dryness, fatigue, and mental discomfort (Liu 2019)